SCIENCE BEHIND NANO GOLD — Gold Nanoparticles in Biology and Medicine: Recent Advances and Prospects

Very extensive research paper, 250 footnotes / sources.

Articles from Acta Naturae are provided here courtesy of National Research University Higher School of Economics

Functionalized gold nanoparticles with controlled geometrical and optical properties are the subject of intensive studies and biomedical applications, including genomics, biosensorics, immunoassays, clinical chemistry, laser phototherapy of cancer cells and tumors, the targeted delivery of drugs, DNA and antigens, optical bioimaging and the monitoring of cells and tissues with the use of state-of-the-art detection systems. This work will provide an overview of the recent advances and current challenges facing the biomedical application of gold nanoparticles of various sizes, shapes, and structures. The review is focused on the application of gold nanoparticle conjugates in biomedical diagnostics and analytics, photothermal and photodynamic therapies, as a carrier for delivering target molecules, and on the immunological and toxicological properties. Keeping in mind the huge volume and high speed of the data update rate, 2/3 of our reference list (certainly restricted to 250 Refs.) includes publications encompassing the past 5 years.

Paper dated 2011

SCIENCE BEHIND SKIN GROWTH, HEALING — Article from Clinical, Cosmetic and Investigational Dermatology — Skin rejuvenation using cosmetic products … a review of the literature

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Skin aging is primarily due to alterations in the dermal extracellular matrix, especially a decrease in collagen I content, fragmentation of collagen fibrils, and accumulation of amorphous elastin material, also known as elastosis. Growth factors and cytokines are included in several cosmetic products intended for skin rejuvenation because of their ability to promote collagen synthesis. Matrikines and matrikine-like peptides offer the advantage of growth factor-like activities but better skin penetration due to their much smaller molecular size. In this review, we summarize the commercially available products containing growth factors, cytokines, and matrikines for which there is evidence that they promote skin rejuvenation.

Gold Nanoparticles & The Future of Medical Diagnostics – Chad Mirkin – NANOSPHERE

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“When you arrange DNA in this format [as helical strands attached by-end to points on a nano gold cluster / sphere], you get an interesting property where these types of structures will [freely enter human cells]; whereas linear DNA [will be blocked by the cell wall]. … Once you can get these types of structures inside cells, you now can begin to flip genetic switches [i.e., modify DNA from within the cell]…”

This was already well underway in 2012.

Gold Nanoparticles Webinar: Strange properties and applications

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Expedeon Published on Jul 22, 2013 Gold nanoparticles exhibit extraordinary properties quite unlike those of the bulk metal. These properties can be exploited in a variety of assay applications, including lateral flow tests, microscopy, flow cytometry and FRET assays. There are also a number of therapeutic applications, especially in the field of cancer. This free … Read more